Southern
vs 
Iowa State
4 meetings · Southern 0-3
| Date | Opponent | Score | Line | O/U | |
|---|---|---|---|---|---|
| Nov 10, 2026 | @ Iowa State
|
||||
| Dec 9, 2018 | @ Iowa State
|
L | 65–101 | ||
| Dec 14, 2014 | @ Iowa State
|
L | 78–88 | ||
| Nov 9, 2012 | @ Iowa State
|
L | 59–82 |