Clemson
vs 
Louisville
17 meetings · Clemson 7-9
| Date | Opponent | Score | Line | O/U | |
|---|---|---|---|---|---|
| Mar 6, 2027 | @ Louisville
|
||||
| Feb 28, 2026 | vs Louisville
|
W | 80–75 | ||
| Mar 14, 2025 | vs Louisville
|
L | 73–76 | ||
| Jan 7, 2025 | @ Louisville
|
L | 64–74 | ||
| Jan 30, 2024 | vs Louisville
|
W | 70–64 | ||
| Feb 18, 2023 | @ Louisville
|
L | 73–83 | ||
| Jan 11, 2023 | vs Louisville
|
W | 83–70 | ||
| Feb 19, 2022 | @ Louisville
|
L | 61–70 | ||
| Jan 27, 2021 | vs Louisville
|
W | 54–50 | ||
| Feb 15, 2020 | vs Louisville
|
W | 77–62 | ||
| Jan 25, 2020 | @ Louisville
|
L | 62–80 | ||
| Feb 16, 2019 | @ Louisville
|
L | 55–56 | ||
| Jan 6, 2018 | vs Louisville
|
W | 74–69 | ||
| Jan 19, 2017 | @ Louisville
|
L | 60–92 | ||
| Jan 10, 2016 | vs Louisville
|
W | 66–62 | ||
| Jan 7, 2015 | @ Louisville
|
L | 52–58 | ||
| Mar 20, 2006 | @ Louisville
|
L | 68–74 |